Ascotoxin (Decumbin), a Metabolite of Ascochyta imperfecta PECK

Quotients of Peck Posets

An elementary, self-contained proof of a result of Pouzet and Rosenberg and of Harper is given. This result states that the quotient of certain posets (called unitary Peck) by a finite group of automorphisms retains some nice properties, including the Sperner property. Examples of unitary Peck posets are given, and the techniques developed here are used to prove a result of Lovhz on the edge-re...

Molecular Characterization of a Fungus Producing Membrane Active Metabolite and Analysis of the Produced Secondary Metabolite

Background: The majority of studies on soil Aspergillus concern the isolation and characterization of the antimicrobial compounds produced by this organism. Our previous studies indicated an isolated Aspergillus strain soil to be of interest, and this subject is further investigated here. Method:  Soil samples of various locations in Iran were collected. Extract from Aspergillus sp. culture was...

Chemical Components of Paecilomyces tenuipes (Peck) Samson

The caterpillar-shaped Chinese medicinal mushroom (DongChongXiaCao) looks like a worm in the winter and like a grass in the summer. The fruiting body has been regarded as popular folk or effective medicines used to treat human diseases such as asthma, bronchial and lung inflammation, and kidney disease. The fruiting bodies of Paecilomyces tenuipes that formed on the living silkworm (Bombyx mori...

Editorial: Advances in Ascochyta Research

Preparation of a Major Metabolite of Iguratimod and Simultaneous Assay of Iguratimod and Its Metabolite by HPLC in Rat Plasma

Iguratimod is a new synthetic disease-modifying antirheumatic drug intended to treat patients with rheumatoid arthritis. A new method using recombinant human CYP450s yeast cells containing c-DNA expressed P450s was applied to identify the metabolic pathways of iguratimod and to prepare its metabolite. The metabolite was isolated, and its structure was identified by quadrupole time-of-flight-mas...